Experience-dependent expression of miR-132 regulates ocular dominance plasticity
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چکیده
منابع مشابه
Mechanisms of Ocular Dominance Plasticity
Preface Have you ever realized that the language you have learned when you were young, the language you grew up with, will always be more permanent then any language you learn later in life? It does not matter what language you come in contact with in the rest of your lifetime, or how well you understand the ins and outs of such communication. You will think, write and talk in your native langu...
متن کاملNMDA Receptor-Dependent Ocular Dominance Plasticity in Adult Visual Cortex
The binocular region of mouse visual cortex is strongly dominated by inputs from the contralateral eye. Here we show in adult mice that depriving the dominant contralateral eye of vision leads to a persistent, NMDA receptor-dependent enhancement of the weak ipsilateral-eye inputs. These data provide in vivo evidence for metaplasticity as a mechanism for binocular competition and demonstrate tha...
متن کاملAge-Dependent Ocular Dominance Plasticity in Adult Mice
BACKGROUND Short monocular deprivation (4 days) induces a shift in the ocular dominance of binocular neurons in the juvenile mouse visual cortex but is ineffective in adults. Recently, it has been shown that an ocular dominance shift can still be elicited in young adults (around 90 days of age) by longer periods of deprivation (7 days). Whether the same is true also for fully mature animals is ...
متن کاملDistinctive features of adult ocular dominance plasticity.
Sensory experience profoundly shapes neural circuitry of juvenile brain. Although the visual cortex of adult rodents retains a capacity for plasticity in response to monocular visual deprivation, the nature of this plasticity and the neural circuit changes that accompany it remain enigmatic. Here, we investigate differences between adult and juvenile ocular dominance plasticity using Fourier op...
متن کاملOcular Dominance Plasticity in Mature Mice
Ocular dominance plasticity, classically thought to be restricted to an early critical period, is now described by Sawtell et al. in fully adult mice. Adult plasticity, like critical period plasticity, requires cortical NMDA receptors but involves different functional changes in cortical circuits.
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2011
ISSN: 1097-6256,1546-1726
DOI: 10.1038/nn.2920